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In this section: Drug Safety and Availability

Food and Drug Administration Overdose Prevention Framework

Overdose Prevention Activities

The FDA Overdose Prevention Framework consists of four overarching priorities that align with the U.S. Department of Health & Human Services' Overdose Prevention Strategy to address the public health emergency as it continues to evolve. The overdose crisis is an evolving public health crisis; as such, FDA continues to evaluate our approach and make adjustments according to the latest available science and data.

FDA Overdose Prevention Framework

FDA’s Overdose Prevention Framework Priorities

Supporting primary prevention by eliminating unnecessary initial prescription drug exposure and inappropriate prolonged prescribing.
Encouraging harm reduction through innovation and education.
Advancing development of evidence-based treatments for substance use disorders.
Protecting the public from unapproved, diverted, or counterfeit drugs presenting overdose risks.

Chronological information about significant FDA activities related to substance use and overdose prevention.